Proliferation markers in tumours: interpretation and clinical value
نویسندگان
چکیده
منابع مشابه
Proliferation markers in tumours: interpretation and clinical value.
Proliferation is one of the most fundamental of biological processes because of its role in growth and in the maintenance of tissue homeostasis. In tumours especially, proliferation has traditionally received much attention. On the one hand, proliferation has been studied as an important cell biological mechanism in oncogenesis, often using rather laborious methods applicable only in experiment...
متن کامل“Rusterholz” Ulcer in Culling Lame Cows: Clinical and Radiographic Interpretation
Objective- To investigate and quantitate radiological and clinical changes in tissues and structures of the claws affected by Rusterholz ulcer. Design- Cross-sectional and Descriptive study Animal- Seven culled lame cows were affected with “Rusterholz” ulcer Procedures- Forty one culled lame cows of 1135 culled cows having digital disorders which were randomly selected for clinical and r...
متن کاملOncogenes, growth factors, receptor expression and proliferation markers in digestive neuroendocrine tumours. A critical reappraisal.
BACKGROUND The main characteristic of the digestive neuroendocrine tumours (dNETs) is the low proliferating activity, even in the presence of malignant, metastatic behavior. PATIENTS AND METHODS Considering that dNETs are rare diseases, relatively numerous studies, often including a conspicuous number of patients, have recently investigated the molecular mechanisms of neuroendocrine tumour ge...
متن کاملGenetic markers in oligodendroglial tumours
BACKGROUND Oliogodendrogliomas are brain tumours composed of the cells resembling oligodendrocytes. They represent the third most common glial tumour, comprising 2.5% of all primary brain tumours and 5-20% of all gliomas. CONCLUSIONS Oligodendroglial tumours with 1p and 19q loss demonstrate a better overall prognosis due to more indolent clinical behaviour and higher sensitivity to treatment....
متن کاملCD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers
BACKGROUND Cutaneous mast cell tumours are one of the most common neoplasms in dogs and show a highly variable biologic behaviour. Several prognosis tools have been proposed for canine mast cell tumours, including histological grading and cell proliferation markers. CD117 is a receptor tyrosine kinase thought to play a key role in human and canine mast cell neoplasms. Normal (membrane-associate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1998
ISSN: 0021-9746
DOI: 10.1136/jcp.51.10.716